In Vitro Priming Recapitulates In Vivo HIV-1 Specific T Cell Responses, Revealing Rapid Loss of Virus Reactive CD4(+) T Cells in Acute HIV-1 Infection

BACKGROUND: The requirements for priming of HIV-specific T cell responses initially seen in infected individuals remain to be defined. Activation of T cell responses in lymph nodes requires cell-cell contact between T cells and DCs, which can give concurrent activation of T cells and HIV transmissio...

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Detalles Bibliográficos
Autores principales: Lubong Sabado, Rachel, Kavanagh, Daniel G., Kaufmann, Daniel E., Fru, Karlhans, Babcock, Ethan, Rosenberg, Eric, Walker, Bruce, Lifson, Jeffrey, Bhardwaj, Nina, Larsson, Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626278/
https://www.ncbi.nlm.nih.gov/pubmed/19165342
http://dx.doi.org/10.1371/journal.pone.0004256

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