Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus

BACKGROUND: Although disease remission can frequently be achieved for patients with neuroblastoma, relapse is common. The cancer stem cell theory suggests that rare tumorigenic cells, resistant to conventional therapy, are responsible for relapse. If true for neuroblastoma, improved cure rates may o...

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Detalles Bibliográficos
Autores principales: Mahller, Yonatan Y., Williams, Jon P., Baird, William H., Mitton, Bryan, Grossheim, Jonathan, Saeki, Yoshinaga, Cancelas, Jose A., Ratner, Nancy, Cripe, Timothy P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626279/
https://www.ncbi.nlm.nih.gov/pubmed/19156211
http://dx.doi.org/10.1371/journal.pone.0004235

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