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The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile

BACKGROUND: Cytochrome P450 (CYP) enzyme 2J2, an epoxygenase predominantly expressed in the heart, metabolises arachidonic acid to biologically active eicosanoids. One of the CYP2J2 products, 11, 12-epoxyeicosatrienoic acid, has several vasoprotective effects. The CYP2J2-G-50T-promotor polymorphism...

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Detalles Bibliográficos
Autores principales:	Börgel, Jan, Bulut, Daniel, Hanefeld, Christoph, Neubauer, Horst, Mügge, Andreas, Epplen, Jörg T, Holland-Letz, Tim, Spiecker, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626571/ https://www.ncbi.nlm.nih.gov/pubmed/19105833 http://dx.doi.org/10.1186/1471-2261-8-41

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