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Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro

BACKGROUND: IQGAP1 is a scaffolding protein and overexpressed in many human tumors, including ovarian cancer. However, the contribution of IQGAP1 to invasive properties of ovarian cancer cells remains unknown. Here, we investigated the effect of IQGAP1-specific short hairpin RNA (shRNA) expressing p...

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Detalles Bibliográficos
Autores principales: Dong, Pei-Xin, Jia, Nan, Xu, Zhu-Jie, Liu, Ying-Tao, Li, Da-Jin, Feng, You-Ji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626583/
https://www.ncbi.nlm.nih.gov/pubmed/19036171
http://dx.doi.org/10.1186/1756-9966-27-77

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