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Protein Functional Surfaces: Global Shape Matching and Local Spatial Alignments of Ligand Binding Sites

BACKGROUND: Protein surfaces comprise only a fraction of the total residues but are the most conserved functional features of proteins. Surfaces performing identical functions are found in proteins absent of any sequence or fold similarity. While biochemical activity can be attributed to a few key r...

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Detalles Bibliográficos
Autores principales: Binkowski, T Andrew, Joachimiak, Andrzej
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626596/
https://www.ncbi.nlm.nih.gov/pubmed/18954462
http://dx.doi.org/10.1186/1472-6807-8-45

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