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Rcan1 negatively regulates FcεRI-mediated signaling and mast cell function

Aggregation of the high affinity IgE receptor (FcεRI) activates a cascade of signaling events leading to mast cell activation. Subsequently, inhibitory signals are engaged for turning off activating signals. We identified that regulator of calcineurin (Rcan) 1 serves as a negative regulator for turn...

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Detalles Bibliográficos
Autores principales:	Yang, Yong Jun, Chen, Wei, Edgar, Alexander, Li, Bo, Molkentin, Jeffery D., Berman, Jason N., Lin, Tong-Jun
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626669/ https://www.ncbi.nlm.nih.gov/pubmed/19124655 http://dx.doi.org/10.1084/jem.20081140

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