Conjugate vaccines and the carriage of Haemophilus influenzae type b.

Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of co...

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Detalles Bibliográficos
Autor principal: Barbour, M L
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626802/
https://www.ncbi.nlm.nih.gov/pubmed/8903227
Descripción
Sumario:Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of conjugate Hib vaccines in decreasing carriage of Hib. This review explores evidence for this effect, and discusses the possible mechanisms of the mucosal influence of Hib conjugate vaccines.

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