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Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts
OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani un...
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Formato: | Texto |
Lenguaje: | English |
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The Korean Radiological Society
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626818/ https://www.ncbi.nlm.nih.gov/pubmed/17923779 http://dx.doi.org/10.3348/kjr.2007.8.5.372 |
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author | Lee, Chang Hyun Im, Jung-Gi Goo, Jin Mo Lee, Hyun Ju Hong, Sung-Tae Shen, Cheng Hua Chung, Doo Hyun Son, Kyu Ri Chang, Jung Min Eo, Hong |
author_facet | Lee, Chang Hyun Im, Jung-Gi Goo, Jin Mo Lee, Hyun Ju Hong, Sung-Tae Shen, Cheng Hua Chung, Doo Hyun Son, Kyu Ri Chang, Jung Min Eo, Hong |
author_sort | Lee, Chang Hyun |
collection | PubMed |
description | OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. RESULTS: The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. CONCLUSION: The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus. |
format | Text |
id | pubmed-2626818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | The Korean Radiological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-26268182009-02-17 Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts Lee, Chang Hyun Im, Jung-Gi Goo, Jin Mo Lee, Hyun Ju Hong, Sung-Tae Shen, Cheng Hua Chung, Doo Hyun Son, Kyu Ri Chang, Jung Min Eo, Hong Korean J Radiol Original Article OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. RESULTS: The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. CONCLUSION: The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus. The Korean Radiological Society 2007 2007-10-20 /pmc/articles/PMC2626818/ /pubmed/17923779 http://dx.doi.org/10.3348/kjr.2007.8.5.372 Text en Copyright © 2007 The Korean Radiological Society http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lee, Chang Hyun Im, Jung-Gi Goo, Jin Mo Lee, Hyun Ju Hong, Sung-Tae Shen, Cheng Hua Chung, Doo Hyun Son, Kyu Ri Chang, Jung Min Eo, Hong Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title | Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title_full | Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title_fullStr | Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title_full_unstemmed | Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title_short | Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts |
title_sort | serial ct findings of paragonimus infested dogs and the micro-ct findings of the worm cysts |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626818/ https://www.ncbi.nlm.nih.gov/pubmed/17923779 http://dx.doi.org/10.3348/kjr.2007.8.5.372 |
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