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Influence of Aromatic and Aliphatic Moieties on Thrombin Inhibitors Potency
Thrombin is a plasma serine protease that plays a key role in coagulation and hemostasis but also in thromboembolic diseases. Direct thrombin inhibitors could be beneficial for future anticoagulant therapy in the prophylaxis of venous and arterial thrombosis as well as myocardial infarction. To desi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Open
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627521/ https://www.ncbi.nlm.nih.gov/pubmed/19238188 http://dx.doi.org/10.2174/1874091X00802010143 |