Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.

Three outbreaks of Ebola hemorrhagic fever have recently occurred in Gabon. Virus has been isolated from clinical materials from all three outbreaks, and nucleotide sequence analysis of the glycoprotein gene of the isolates and virus present in clinical samples has been carried out. These data indic...

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Autores principales: Georges-Courbot, M C, Sanchez, A, Lu, C Y, Baize, S, Leroy, E, Lansout-Soukate, J, Tévi-Bénissan, C, Georges, A J, Trappier, S G, Zaki, S R, Swanepoel, R, Leman, P A, Rollin, P E, Peters, C J, Nichol, S T, Ksiazek, T G
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627600/
https://www.ncbi.nlm.nih.gov/pubmed/9126445
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author Georges-Courbot, M C
Sanchez, A
Lu, C Y
Baize, S
Leroy, E
Lansout-Soukate, J
Tévi-Bénissan, C
Georges, A J
Trappier, S G
Zaki, S R
Swanepoel, R
Leman, P A
Rollin, P E
Peters, C J
Nichol, S T
Ksiazek, T G
author_facet Georges-Courbot, M C
Sanchez, A
Lu, C Y
Baize, S
Leroy, E
Lansout-Soukate, J
Tévi-Bénissan, C
Georges, A J
Trappier, S G
Zaki, S R
Swanepoel, R
Leman, P A
Rollin, P E
Peters, C J
Nichol, S T
Ksiazek, T G
author_sort Georges-Courbot, M C
collection PubMed
description Three outbreaks of Ebola hemorrhagic fever have recently occurred in Gabon. Virus has been isolated from clinical materials from all three outbreaks, and nucleotide sequence analysis of the glycoprotein gene of the isolates and virus present in clinical samples has been carried out. These data indicate that each of the three outbreaks should be considered an independent emergence of a different Ebola virus of the Zaire subtype. As in earlier Ebola virus outbreaks, no genetic variability was detected between virus samples taken during an individual outbreak.
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spelling pubmed-26276002009-05-20 Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon. Georges-Courbot, M C Sanchez, A Lu, C Y Baize, S Leroy, E Lansout-Soukate, J Tévi-Bénissan, C Georges, A J Trappier, S G Zaki, S R Swanepoel, R Leman, P A Rollin, P E Peters, C J Nichol, S T Ksiazek, T G Emerg Infect Dis Research Article Three outbreaks of Ebola hemorrhagic fever have recently occurred in Gabon. Virus has been isolated from clinical materials from all three outbreaks, and nucleotide sequence analysis of the glycoprotein gene of the isolates and virus present in clinical samples has been carried out. These data indicate that each of the three outbreaks should be considered an independent emergence of a different Ebola virus of the Zaire subtype. As in earlier Ebola virus outbreaks, no genetic variability was detected between virus samples taken during an individual outbreak. Centers for Disease Control and Prevention 1997 /pmc/articles/PMC2627600/ /pubmed/9126445 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Article
Georges-Courbot, M C
Sanchez, A
Lu, C Y
Baize, S
Leroy, E
Lansout-Soukate, J
Tévi-Bénissan, C
Georges, A J
Trappier, S G
Zaki, S R
Swanepoel, R
Leman, P A
Rollin, P E
Peters, C J
Nichol, S T
Ksiazek, T G
Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title_full Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title_fullStr Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title_full_unstemmed Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title_short Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon.
title_sort isolation and phylogenetic characterization of ebola viruses causing different outbreaks in gabon.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627600/
https://www.ncbi.nlm.nih.gov/pubmed/9126445
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