Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.

In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Although not all potential surveillance artifacts could be excluded, it is highly probable that the data reflect a true outbreak. However, the cause of this increase h...

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Detalles Bibliográficos
Autores principales: de Melker, H E, Conyn-van Spaendonck, M A, Rümke, H C, van Wijngaarden, J K, Mooi, F R, Schellekens, J F
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627603/
https://www.ncbi.nlm.nih.gov/pubmed/9204299
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author de Melker, H E
Conyn-van Spaendonck, M A
Rümke, H C
van Wijngaarden, J K
Mooi, F R
Schellekens, J F
author_facet de Melker, H E
Conyn-van Spaendonck, M A
Rümke, H C
van Wijngaarden, J K
Mooi, F R
Schellekens, J F
author_sort de Melker, H E
collection PubMed
description In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Although not all potential surveillance artifacts could be excluded, it is highly probable that the data reflect a true outbreak. However, the cause of this increase has not yet been determined. Further research is directed to the severity of disease and a possible mismatch between the vaccine and the circulating Bordetella strains.
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spelling pubmed-26276032009-05-20 Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine. de Melker, H E Conyn-van Spaendonck, M A Rümke, H C van Wijngaarden, J K Mooi, F R Schellekens, J F Emerg Infect Dis Research Article In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Although not all potential surveillance artifacts could be excluded, it is highly probable that the data reflect a true outbreak. However, the cause of this increase has not yet been determined. Further research is directed to the severity of disease and a possible mismatch between the vaccine and the circulating Bordetella strains. Centers for Disease Control and Prevention 1997 /pmc/articles/PMC2627603/ /pubmed/9204299 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Article
de Melker, H E
Conyn-van Spaendonck, M A
Rümke, H C
van Wijngaarden, J K
Mooi, F R
Schellekens, J F
Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title_full Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title_fullStr Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title_full_unstemmed Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title_short Pertussis in The Netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
title_sort pertussis in the netherlands: an outbreak despite high levels of immunization with whole-cell vaccine.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627603/
https://www.ncbi.nlm.nih.gov/pubmed/9204299
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