Cargando…

Phthalates Impair Germ Cell Development in the Human Fetal Testis in Vitro without Change in Testosterone Production

BACKGROUND: Several studies have described an increasing frequency of male reproductive disorders, which may have a common origin in fetal life and which are hypothesized to be caused by endocrine disruptors. Phthalate esters represent a class of environmental endocrine-active chemicals known to dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lambrot, Romain, Muczynski, Vincent, Lécureuil, Charlotte, Angenard, Gaëlle, Coffigny, Hervé, Pairault, Catherine, Moison, Delphine, Frydman, René, Habert, René, Rouiller-Fabre, Virginie
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627862/ https://www.ncbi.nlm.nih.gov/pubmed/19165384 http://dx.doi.org/10.1289/ehp.11146

Ejemplares similares

Cadmium Increases Human Fetal Germ Cell Apoptosis
por: Angenard, Gaëlle, et al.
Publicado: (2010)

Cellular and Molecular Effect of MEHP Involving LXRα in Human Fetal Testis and Ovary
por: Muczynski, Vincent, et al.
Publicado: (2012)

Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors
por: Habert, René, et al.
Publicado: (2014)

Differential Effects of Bisphenol A and Diethylstilbestrol on Human, Rat and Mouse Fetal Leydig Cell Function
por: N’Tumba-Byn, Thierry, et al.
Publicado: (2012)

Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetus
por: Habert, René, et al.
Publicado: (2014)

Nuclear Receptors and Endocrine Disruptors in Fetal and Neonatal Testes: A Gapped Landscape
por: Rouiller-Fabre, Virginie, et al.
Publicado: (2015)

Effects of environmental Bisphenol A exposures on germ cell development and Leydig cell function in the human fetal testis
por: Eladak, Soria, et al.
Publicado: (2018)

Phthalates Impair Germ Cell Number in the Mouse Fetal Testis by an Androgen- and Estrogen-Independent Mechanism
por: Lehraiki, Abdelali, et al.
Publicado: (2009)

Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads
por: Bellutti, Laura, et al.
Publicado: (2019)

Unexpected Interacting Effects of Physical (Radiation) and Chemical (Bisphenol A) Treatments on Male Reproductive Functions in Mice
por: Wieckowski, Margaux, et al.
Publicado: (2021)

Expression and localization of aromatase during fetal mouse testis development
por: Borday, Caroline, et al.
Publicado: (2013)

Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts
por: van den Driesche, Sander, et al.
Publicado: (2014)

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure
por: Whiley, Penny A. F., et al.
Publicado: (2023)

The Testosterone Test: Phthalate Inhibits Leydig Cell Aggregation
por: Barrett, Julia R.
Publicado: (2007)

Gamete Gamble: Phthalate Alters Germ Cell Development
por: Weinhold, Bob
Publicado: (2009)

Health on the Factory Floor: Occupational Phthalate Exposure Reduces Testosterone
por: Barrett, Julia R.
Publicado: (2006)

The Acute Exposure of Human Adult Testis Tissue to Cannabinoids THC and CBD Does Not Impact Testosterone Production Nor Germ Cell Lineage
por: da Silva, Janaina, et al.
Publicado: (2023)

Human Fetal Testis Xenografts Are Resistant to Phthalate-Induced Endocrine Disruption
por: Heger, Nicholas E, et al.
Publicado: (2012)

SUN-217 Alternate Pathways of Testosterone Action in Testis
por: Talapatra, Arpita
Publicado: (2019)

Mouse Testis Development and Function Are Differently Regulated by Follicle-Stimulating Hormone Receptors Signaling During Fetal and Prepubertal Life
por: Migrenne, Stéphanie, et al.
Publicado: (2012)

Retinoic Acid and Germ Cell Development in the Ovary and Testis
por: Endo, Tsutomu, et al.
Publicado: (2019)

Absent Testis With a Mediastinal Germ Cell Tumor
por: Bellur, Shreyas, et al.
Publicado: (2022)

Intrauterine exposure to diethylhexyl phthalate disrupts gap junctions in the fetal rat testis
por: Di Lorenzo, Mariana, et al.
Publicado: (2020)

Exposure to phthalate esters induces an autophagic response in male germ cells
por: Valenzuela-Leon, Paula, et al.
Publicado: (2017)

Biotin Enhances Testosterone Production in Mice and Their Testis-Derived Cells
por: Shiozawa, Kota, et al.
Publicado: (2022)

Effects on the Local Immunity in the Testis by Exposure to Di-(2-ethylhexyl) Phthalate (DEHP) in Mice
por: KITAOKA, Miyuki, et al.
Publicado: (2013)

Tuberculosis in postchemotherapy residual masses in germ cell tumor of the testis
por: Bansal, Rajesh, et al.
Publicado: (2011)

Hedgehog signalling promotes germ cell survival in the rat testis
por: Mäkelä, Juho-Antti, et al.
Publicado: (2011)

N-cadherin expression in malignant germ cell tumours of the testis
por: Bremmer, Felix, et al.
Publicado: (2012)

TAp73 is essential for germ cell adhesion and maturation in testis
por: Holembowski, Lena, et al.
Publicado: (2014)

Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis
por: Bilen, Mehmet Asim, et al.
Publicado: (2016)

Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress
por: Messiaen, S, et al.
Publicado: (2013)

Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats
por: Vo, Thuy TB, et al.
Publicado: (2009)

Ferroptosis is critical for phthalates driving the blood-testis barrier dysfunction via targeting transferrin receptor
por: Zhao, Yi, et al.
Publicado: (2022)

Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia.
por: Klys, H. S., et al.
Publicado: (1992)

Management options for stage 1 nonseminomatous germ cell tumors of the testis
por: Beck, Stephen D. W.
Publicado: (2010)

Germ cell development in the postnatal testis: the key to prevent malignancy in cryptorchidism?
por: Hutson, John M., et al.
Publicado: (2013)

Dual role of immune cells in the testis: Protective or pathogenic for germ cells?
por: Pérez, Cecilia V., et al.
Publicado: (2013)

Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation
por: Tzung, Keh-Weei, et al.
Publicado: (2014)

Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation
por: Tzung, Keh-Weei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tid9bssbe1aaj3c4dnsrarh2t2