Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D

Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region exerts the single strongest effect on genetic risk. Epidemiological data in MS provide strong evidence that environmental factors act at a population level to influence the unusual geographical distribut...

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Detalles Bibliográficos
Autores principales: Ramagopalan, Sreeram V., Maugeri, Narelle J., Handunnetthi, Lahiru, Lincoln, Matthew R., Orton, Sarah-Michelle, Dyment, David A., DeLuca, Gabriele C., Herrera, Blanca M., Chao, Michael J., Sadovnick, A. Dessa, Ebers, George C., Knight, Julian C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627899/
https://www.ncbi.nlm.nih.gov/pubmed/19197344
http://dx.doi.org/10.1371/journal.pgen.1000369

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