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The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer
BACKGROUND: Pancreatic cancer continues to have a 5-year survival of less than 5%. Therefore, more effective therapies are necessary to improve prognosis in this disease. Angiogenesis is required for tumor growth, and subsequently, mediators of angiogenesis are attractive targets for therapy. Vascul...
Autores principales: | Dineen, Sean P, Sullivan, Laura A, Beck, Adam W, Miller, Andrew F, Carbon, Juliet G, Mamluk, Roni, Wong, Henry, Brekken, Rolf A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627916/ https://www.ncbi.nlm.nih.gov/pubmed/19038046 http://dx.doi.org/10.1186/1471-2407-8-352 |
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