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Whi5 Regulation by Site Specific CDK-Phosphorylation in Saccharomyces cerevisiae

The Whi5 transcriptional repressor is a negative regulator of G1 cell cycle progression in Saccharomyces cerevisiae and is functionally equivalent to the Retinoblastoma (Rb) tumor suppressor protein in mammals. In early G1, Whi5 binds to and inhibits SBF (Swi4/Swi6) transcriptional complexes. At Sta...

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Detalles Bibliográficos
Autores principales:	Wagner, Michelle V., Smolka, Marcus B., de Bruin, Rob A. M., Zhou, Huilin, Wittenberg, Curt, Dowdy, Steven F.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627923/ https://www.ncbi.nlm.nih.gov/pubmed/19172996 http://dx.doi.org/10.1371/journal.pone.0004300

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