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A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts
The clinically established proarrhythmic effect of bradycardia and antiarrhythmic effect of lidocaine (10 μM) were reproduced in hypokalaemic (3.0 mM K(+)) Langendorff-perfused murine hearts paced over a range (80–180 ms) of baseline cycle lengths (BCLs). Action potential durations (at 90% repolariz...
Autores principales: | Sabir, Ian N., Fraser, James A., Cass, Thomas R., Grace, Andrew A., Huang, Christopher L.-H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627988/ https://www.ncbi.nlm.nih.gov/pubmed/17437126 http://dx.doi.org/10.1007/s00424-007-0255-x |
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