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The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved
PURPOSE: To identify the incidence of new vertebral compression fractures in women after kyphoplasty and to analyze influential factors in these patients. MATERIALS AND METHODS: One hundred and eleven consecutive female patients with osteoporotic vertebral compression fractures (VCFs) underwent kyph...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Yonsei University College of Medicine
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628047/ https://www.ncbi.nlm.nih.gov/pubmed/17722237 http://dx.doi.org/10.3349/ymj.2007.48.4.645 |
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author | Moon, Eun-Su Kim, Hak-Sun Park, Jin-Oh Moon, Seong-Hwan Lee, Hwan-Mo Shin, Dong-Eun Ha, Jung-Won Ahn, Eun-Kyoung Shim, Dong-Jun Chung, Jun-Young |
author_facet | Moon, Eun-Su Kim, Hak-Sun Park, Jin-Oh Moon, Seong-Hwan Lee, Hwan-Mo Shin, Dong-Eun Ha, Jung-Won Ahn, Eun-Kyoung Shim, Dong-Jun Chung, Jun-Young |
author_sort | Moon, Eun-Su |
collection | PubMed |
description | PURPOSE: To identify the incidence of new vertebral compression fractures in women after kyphoplasty and to analyze influential factors in these patients. MATERIALS AND METHODS: One hundred and eleven consecutive female patients with osteoporotic vertebral compression fractures (VCFs) underwent kyphoplasty at 137 levels. These patients were followed for 15.2 months postoperatively. For the survey of new vertebral compression fractures, medical records and x-rays were reviewed, and telephone interviews were conducted with all patients. RESULTS: During that time 20 (18%) patients developed new VCFs. The rate of occurrence of new VCFs in one year was 15.5% using a Kaplan-Meier curve. Body mass index (BMI), symptom duration and kyphoplasty level were the statistically significant factors between the patient groups both with and without new VCFs after kyphoplasty. In the comparison between the adjacent and remote new VCF groups, the adjacent new VCF group showed a larger amount of polymethyl methacrylate (PMMA) use during kyphoplasty (p < 0.05). Before kyphoplasty, 9.9% of the patients had been prescribed medication for osteoporosis, and 93.7% of the patients started or continued medication after kyphoplasty. The development of new VCFs was affected by the number of vertebrae involved in the kyphoplasty. However, the lower incidence rate (15.5%) of new compression fractures might be due to a greater percentage (93.7% in our study) of patients taking anti-osteoporotic medication before and/or after kyphoplasty. CONCLUSION: When kyphoplasty is planned for the management of patients with osteoporotic VCFs, the application of a small amount of PMMA can be considered in order to lower the risk of new fractures in adjacent vertebrae. The postoperative use of anti- osteoporotic medication is recommended for the prevention of new VCFs. |
format | Text |
id | pubmed-2628047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Yonsei University College of Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-26280472009-02-02 The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved Moon, Eun-Su Kim, Hak-Sun Park, Jin-Oh Moon, Seong-Hwan Lee, Hwan-Mo Shin, Dong-Eun Ha, Jung-Won Ahn, Eun-Kyoung Shim, Dong-Jun Chung, Jun-Young Yonsei Med J Original Article PURPOSE: To identify the incidence of new vertebral compression fractures in women after kyphoplasty and to analyze influential factors in these patients. MATERIALS AND METHODS: One hundred and eleven consecutive female patients with osteoporotic vertebral compression fractures (VCFs) underwent kyphoplasty at 137 levels. These patients were followed for 15.2 months postoperatively. For the survey of new vertebral compression fractures, medical records and x-rays were reviewed, and telephone interviews were conducted with all patients. RESULTS: During that time 20 (18%) patients developed new VCFs. The rate of occurrence of new VCFs in one year was 15.5% using a Kaplan-Meier curve. Body mass index (BMI), symptom duration and kyphoplasty level were the statistically significant factors between the patient groups both with and without new VCFs after kyphoplasty. In the comparison between the adjacent and remote new VCF groups, the adjacent new VCF group showed a larger amount of polymethyl methacrylate (PMMA) use during kyphoplasty (p < 0.05). Before kyphoplasty, 9.9% of the patients had been prescribed medication for osteoporosis, and 93.7% of the patients started or continued medication after kyphoplasty. The development of new VCFs was affected by the number of vertebrae involved in the kyphoplasty. However, the lower incidence rate (15.5%) of new compression fractures might be due to a greater percentage (93.7% in our study) of patients taking anti-osteoporotic medication before and/or after kyphoplasty. CONCLUSION: When kyphoplasty is planned for the management of patients with osteoporotic VCFs, the application of a small amount of PMMA can be considered in order to lower the risk of new fractures in adjacent vertebrae. The postoperative use of anti- osteoporotic medication is recommended for the prevention of new VCFs. Yonsei University College of Medicine 2007-08-31 2007-08-20 /pmc/articles/PMC2628047/ /pubmed/17722237 http://dx.doi.org/10.3349/ymj.2007.48.4.645 Text en Copyright © 2007 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Moon, Eun-Su Kim, Hak-Sun Park, Jin-Oh Moon, Seong-Hwan Lee, Hwan-Mo Shin, Dong-Eun Ha, Jung-Won Ahn, Eun-Kyoung Shim, Dong-Jun Chung, Jun-Young The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title | The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title_full | The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title_fullStr | The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title_full_unstemmed | The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title_short | The Incidence of New Vertebral Compression Fractures in Women after Kyphoplasty and Factors Involved |
title_sort | incidence of new vertebral compression fractures in women after kyphoplasty and factors involved |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628047/ https://www.ncbi.nlm.nih.gov/pubmed/17722237 http://dx.doi.org/10.3349/ymj.2007.48.4.645 |
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