Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress

PURPOSE: Retinitis pigmentosa (RP), a retinal neurodegenerative disorder characterized by apoptosis of photoreceptor cells, is caused by mutations in many different genes. We analyzed the RP gene ceramide kinase-like (CERKL) to determine CERKL function and contribution to pathogenesis. METHODS: RT–P...

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Detalles Bibliográficos
Autores principales: Tuson, Miquel, Garanto, Alejandro, Gonzàlez-Duarte, Roser, Marfany, Gemma
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628313/
https://www.ncbi.nlm.nih.gov/pubmed/19158957

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