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Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts

AIM: To explore the physiological consequences of the ryanodine receptor (RyR2)-P2328S mutation associated with catecholaminergic polymorphic ventricular tachycardia (CPVT). METHODS: We generated heterozygotic (RyR2(p/s)) and homozygotic (RyR2(s/s)) transgenic mice and studied Ca(2+) signals from re...

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Detalles Bibliográficos
Autores principales:	Goddard, C A, Ghais, N S, Zhang, Y, Williams, A J, Colledge, W H, Grace, A A, Huang, C L-H
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Cardiovascular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628439/ https://www.ncbi.nlm.nih.gov/pubmed/18419777 http://dx.doi.org/10.1111/j.1748-1716.2008.01865.x

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