Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses. By screening a diverse synthetic chemical library, we have discovered two novel classes of small molecule...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Baozhi, Dodge, Michael E., Tang, Wei, Lu, Jianming, Ma, Zhiqiang, Fan, Chih-Wei, Wei, Shuguang, Hao, Wayne, Kilgore, Jessica, Williams, Noelle S., Roth, Michael G., Amatruda, James F., Chen, Chuo, Lum, Lawrence
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628455/
https://www.ncbi.nlm.nih.gov/pubmed/19125156
http://dx.doi.org/10.1038/nchembio.137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628455/
https://www.ncbi.nlm.nih.gov/pubmed/19125156
http://dx.doi.org/10.1038/nchembio.137

Ejemplares similares