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Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses. By screening a diverse synthetic chemical library, we have discovered two novel classes of small molecule...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628455/ https://www.ncbi.nlm.nih.gov/pubmed/19125156 http://dx.doi.org/10.1038/nchembio.137 |