Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

OBJECTIVE—To quantitate plasma ceramide subspecies concentrations in obese subjects with type 2 diabetes and relate these plasma levels to the severity of insulin resistance. Ceramides are a putative mediator of insulin resistance and lipotoxicity, and accumulation of ceramides within tissues in obe...

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Detalles Bibliográficos
Autores principales: Haus, Jacob M., Kashyap, Sangeeta R., Kasumov, Takhar, Zhang, Renliang, Kelly, Karen R., DeFronzo, Ralph A., Kirwan, John P.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628606/
https://www.ncbi.nlm.nih.gov/pubmed/19008343
http://dx.doi.org/10.2337/db08-1228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628606/
https://www.ncbi.nlm.nih.gov/pubmed/19008343
http://dx.doi.org/10.2337/db08-1228

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