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Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

OBJECTIVE— Somatostatin (SST) is secreted by islet δ-cells and by extraislet neuroendocrine cells. SST receptors have been identified on α- and β-cells, and exogenous SST inhibits insulin and glucagon secretion, consistent with a role for SST in regulating α- and β-cell function. However, the specif...

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Detalles Bibliográficos
Autores principales:	Hauge-Evans, Astrid C., King, Aileen J., Carmignac, Danielle, Richardson, Carolyn C., Robinson, Iain C.A.F., Low, Malcolm J., Christie, Michael R., Persaud, Shanta J., Jones, Peter M.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628614/ https://www.ncbi.nlm.nih.gov/pubmed/18984743 http://dx.doi.org/10.2337/db08-0792

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