Roles of IP(3)R and RyR Ca(2+) Channels in Endoplasmic Reticulum Stress and β-Cell Death

OBJECTIVE—Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of diabetes, but the roles of specific ER Ca(2+) release channels in the ER stress–associated apoptosis pathway remain unknown. Here, we examined the effects of stimulating or inhibiting the ER-resident inositol tris...

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Detalles Bibliográficos
Autores principales: Luciani, Dan S., Gwiazda, Kamila S., Yang, Ting-Lin B., Kalynyak, Tatyana B., Bychkivska, Yaryna, Frey, Matthew H.Z., Jeffrey, Kristin D., Sampaio, Arthur V., Underhill, T. Michael, Johnson, James D.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628616/
https://www.ncbi.nlm.nih.gov/pubmed/19033399
http://dx.doi.org/10.2337/db07-1762

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