Cargando…

A Role for von Hippel-Lindau Protein in Pancreatic β-Cell Function

OBJECTIVE—The Vhlh gene codes for the von Hippel-Lindau protein (VHL), a tumor suppressor that is a key player in the cellular response to oxygen sensing. In humans, a germline mutation in the VHL gene leads to the von Hippel-Lindau disease, a familial syndrome characterized by benign and malignant...

Descripción completa

Detalles Bibliográficos
Autores principales: Puri, Sapna, Cano, David A., Hebrok, Matthias
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628617/
https://www.ncbi.nlm.nih.gov/pubmed/19033400
http://dx.doi.org/10.2337/db08-0749