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Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats

BACKGROUND: The glial glutamate transporter GLT-1 is abundantly expressed in astrocytes and is crucial for glutamate removal from the synaptic cleft. Decreases in glutamate uptake activity and expression of spinal glutamate transporters are reported in animal models of pathological pain. However, th...

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Detalles Bibliográficos
Autores principales:	Maeda, Sanae, Kawamoto, Ai, Yatani, Yumi, Shirakawa, Hisashi, Nakagawa, Takayuki, Kaneko, Shuji
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628654/ https://www.ncbi.nlm.nih.gov/pubmed/19108711 http://dx.doi.org/10.1186/1744-8069-4-65

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