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IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13

BACKGROUND: IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of transcription 6 (STAT6). The IL-13Rα2 receptor may a...

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Detalles Bibliográficos
Autores principales:	Moynihan, Barry J, Tolloczko, Barbara, Bassam, Souad El, Ferraro, Pascale, Michoud, Marie-Claire, Martin, James G, Laberge, Sophie
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628656/ https://www.ncbi.nlm.nih.gov/pubmed/19116009 http://dx.doi.org/10.1186/1465-9921-9-84

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