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Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics

Because of the limited processing capacity of eyes, retinal networks must adapt constantly to best present the ever changing visual world to the brain. However, we still know little about how adaptation in retinal networks shapes neural encoding of changing information. To study this question, we re...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Nikolaev, Anton, Wardill, Trevor J., O'Kane, Cahir J., de Polavieja, Gonzalo G., Juusola, Mikko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628724/
https://www.ncbi.nlm.nih.gov/pubmed/19180196
http://dx.doi.org/10.1371/journal.pone.0004307
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author Zheng, Lei
Nikolaev, Anton
Wardill, Trevor J.
O'Kane, Cahir J.
de Polavieja, Gonzalo G.
Juusola, Mikko
author_facet Zheng, Lei
Nikolaev, Anton
Wardill, Trevor J.
O'Kane, Cahir J.
de Polavieja, Gonzalo G.
Juusola, Mikko
author_sort Zheng, Lei
collection PubMed
description Because of the limited processing capacity of eyes, retinal networks must adapt constantly to best present the ever changing visual world to the brain. However, we still know little about how adaptation in retinal networks shapes neural encoding of changing information. To study this question, we recorded voltage responses from photoreceptors (R1–R6) and their output neurons (LMCs) in the Drosophila eye to repeated patterns of contrast values, collected from natural scenes. By analyzing the continuous photoreceptor-to-LMC transformations of these graded-potential neurons, we show that the efficiency of coding is dynamically improved by adaptation. In particular, adaptation enhances both the frequency and amplitude distribution of LMC output by improving sensitivity to under-represented signals within seconds. Moreover, the signal-to-noise ratio of LMC output increases in the same time scale. We suggest that these coding properties can be used to study network adaptation using the genetic tools in Drosophila, as shown in a companion paper (Part II).
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spelling pubmed-26287242009-01-30 Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics Zheng, Lei Nikolaev, Anton Wardill, Trevor J. O'Kane, Cahir J. de Polavieja, Gonzalo G. Juusola, Mikko PLoS One Research Article Because of the limited processing capacity of eyes, retinal networks must adapt constantly to best present the ever changing visual world to the brain. However, we still know little about how adaptation in retinal networks shapes neural encoding of changing information. To study this question, we recorded voltage responses from photoreceptors (R1–R6) and their output neurons (LMCs) in the Drosophila eye to repeated patterns of contrast values, collected from natural scenes. By analyzing the continuous photoreceptor-to-LMC transformations of these graded-potential neurons, we show that the efficiency of coding is dynamically improved by adaptation. In particular, adaptation enhances both the frequency and amplitude distribution of LMC output by improving sensitivity to under-represented signals within seconds. Moreover, the signal-to-noise ratio of LMC output increases in the same time scale. We suggest that these coding properties can be used to study network adaptation using the genetic tools in Drosophila, as shown in a companion paper (Part II). Public Library of Science 2009-01-30 /pmc/articles/PMC2628724/ /pubmed/19180196 http://dx.doi.org/10.1371/journal.pone.0004307 Text en Zheng et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Zheng, Lei
Nikolaev, Anton
Wardill, Trevor J.
O'Kane, Cahir J.
de Polavieja, Gonzalo G.
Juusola, Mikko
Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title_full Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title_fullStr Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title_full_unstemmed Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title_short Network Adaptation Improves Temporal Representation of Naturalistic Stimuli in Drosophila Eye: I Dynamics
title_sort network adaptation improves temporal representation of naturalistic stimuli in drosophila eye: i dynamics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628724/
https://www.ncbi.nlm.nih.gov/pubmed/19180196
http://dx.doi.org/10.1371/journal.pone.0004307
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