M-CSF and GM-CSF Regulation of STAT5 Activation and DNA Binding in Myeloid Cell Differentiation is Disrupted in Nonobese Diabetic Mice

Defects in macrophage colony-stimulating factor (M-CSF) signaling disrupt myeloid cell differentiation in nonobese diabetic (NOD) mice, blocking myeloid maturation into tolerogenic antigen-presenting cells (APCs). In the absence of M-CSF signaling, NOD myeloid cells have abnormally high granulocyte...

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Detalles Bibliográficos
Autores principales: Rumore-Maton, B., Elf, J., Belkin, N., Stutevoss, B., Seydel, F., Garrigan, E., Litherland, S. A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628775/
https://www.ncbi.nlm.nih.gov/pubmed/19165346
http://dx.doi.org/10.1155/2008/769795

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