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Methylation-sensitive linking libraries enhance gene-enriched sequencing of complex genomes and map DNA methylation domains
BACKGROUND: Many plant genomes are resistant to whole-genome assembly due to an abundance of repetitive sequence, leading to the development of gene-rich sequencing techniques. Two such techniques are hypomethylated partial restriction (HMPR) and methylation spanning linker libraries (MSLL). These l...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628917/ https://www.ncbi.nlm.nih.gov/pubmed/19099592 http://dx.doi.org/10.1186/1471-2164-9-621 |