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Immunological tolerance and tumor rejection in embryo-aggregated chimeric mice – Lessons for tumor immunity

BACKGROUND: Rejection of transplanted tumors by the immune system is a rare event in syngeneic hosts, and is considered to be dependent on the local interaction of defensive immune reactions and tumor tolerance mechanisms. Here, we have enlisted the aid of a unique set of embryo-aggregated lineage c...

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Detalles Bibliográficos
Autores principales: Wagner, Alexander Y, Holle, Eric, Holle, Lori, Yu, Xianzhong, Schwamberger, Günter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628932/
https://www.ncbi.nlm.nih.gov/pubmed/19087311
http://dx.doi.org/10.1186/1471-2407-8-370