First isolation of two colistin-resistant emerging pathogens, Brevundimonas diminuta and Ochrobactrum anthropi, in a woman with cystic fibrosis: a case report

INTRODUCTION: Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of human infections. CASE PRESENTATION: We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimo...

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Detalles Bibliográficos
Autores principales: Menuet, Magalie, Bittar, Fadi, Stremler, Nathalie, Dubus, Jean-Christophe, Sarles, Jacques, Raoult, Didier, Rolain, Jean-Marc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628933/
https://www.ncbi.nlm.nih.gov/pubmed/19061488
http://dx.doi.org/10.1186/1752-1947-2-373
Descripción
Sumario:INTRODUCTION: Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of human infections. CASE PRESENTATION: We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimonas diminuta and Ochrobactrum anthropi, in a 17-year-old woman with cystic fibrosis and pneumonia. The patient eventually responded well to a 2-week regime of imipenem and tobramycin. CONCLUSION: Our results clearly re-emphasize the emergence of new colistin-resistant pathogens in patients with cystic fibrosis.

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