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Substrate Specificity of the Oxidoreductase ERp57 Is Determined Primarily by Its Interaction with Calnexin and Calreticulin

The formation of disulfides within proteins entering the secretory pathway is catalyzed by the protein disulfide isomerase family of endoplasmic reticulum localized oxidoreductases. One such enzyme, ERp57, is thought to catalyze the isomerization of non-native disulfide bonds formed in glycoproteins...

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Detalles Bibliográficos
Autores principales:	Jessop, Catherine E., Tavender, Timothy J., Watkins, Rachel H., Chambers, Joseph E., Bulleid, Neil J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629083/ https://www.ncbi.nlm.nih.gov/pubmed/19054761 http://dx.doi.org/10.1074/jbc.M808054200

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