Hepatitis C Virus Is a Weak Inducer of Interferon Alpha in Plasmacytoid Dendritic Cells in Comparison with Influenza and Human Herpesvirus Type-1

Plasmacytoid dendritic cells (pDCs) are responsible for the production of type I IFN during viral infection. Viral elimination by IFN-α-based therapy in more than 50% of patients chronically infected with hepatitis C virus (HCV) suggests a possible impairment of production of endogenous IFN-α by pDC...

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Detalles Bibliográficos
Autores principales: Gondois-Rey, Françoise, Dental, Clélia, Halfon, Philippe, Baumert, Thomas F., Olive, Daniel, Hirsch, Ivan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629532/
https://www.ncbi.nlm.nih.gov/pubmed/19183807
http://dx.doi.org/10.1371/journal.pone.0004319

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