Elevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells

PURPOSE: This study was conducted to determine whether elevated hydrostatic pressure alters mitochondrial structure, triggers release of the dynamin-related guanosine triphosphatase (GTPase) optic atrophy type 1 (OPA1) or cytochrome C from mitochondria, alters OPA1 gene expression, and can directly...

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Detalles Bibliográficos
Autores principales: Ju, Won-Kyu, Kim, Keun-Young, Lindsey, James D., Angert, Mila, Patel, Ankur, Scott, Ray T., Liu, Quan, Crowston, Jonathan G., Ellisman, Mark H., Perkins, Guy A., Weinreb, Robert N.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629709/
https://www.ncbi.nlm.nih.gov/pubmed/19169378

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