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Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation

BACKGROUND: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent results indicate that not only the presence of a motif but also motif context (for example the orientation of a motif or its...

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Detalles Bibliográficos
Autores principales:	Westholm, Jakub Orzechowski, Xu, Feifei, Ronne, Hans, Komorowski, Jan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629780/ https://www.ncbi.nlm.nih.gov/pubmed/19014636 http://dx.doi.org/10.1186/1471-2105-9-484

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