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ACC2 Is Expressed at High Levels Human White Adipose and Has an Isoform with a Novel N-Terminus

Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled wi...

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Detalles Bibliográficos
Autores principales: Castle, John C., Hara, Yoshikazu, Raymond, Christopher K., Garrett-Engele, Philip, Ohwaki, Kenji, Kan, Zhengyan, Kusunoki, Jun, Johnson, Jason M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629817/
https://www.ncbi.nlm.nih.gov/pubmed/19190759
http://dx.doi.org/10.1371/journal.pone.0004369