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ACC2 Is Expressed at High Levels Human White Adipose and Has an Isoform with a Novel N-Terminus
Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled wi...
Autores principales: | Castle, John C., Hara, Yoshikazu, Raymond, Christopher K., Garrett-Engele, Philip, Ohwaki, Kenji, Kan, Zhengyan, Kusunoki, Jun, Johnson, Jason M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629817/ https://www.ncbi.nlm.nih.gov/pubmed/19190759 http://dx.doi.org/10.1371/journal.pone.0004369 |
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