Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei

Genetic research into the select agents Burkholderia pseudomallei and B. mallei is currently hampered by a paucity of approved antimicrobial drug–selection markers. The strict regulations imposed on researchers in the United States but not in other parts of the world lead to discrepancies in practic...

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Detalles Bibliográficos
Autores principales: Schweizer, Herbert P., Peacock, Sharon J.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630740/
https://www.ncbi.nlm.nih.gov/pubmed/18976550
http://dx.doi.org/10.3201/eid1411.080431
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author Schweizer, Herbert P.
Peacock, Sharon J.
author_facet Schweizer, Herbert P.
Peacock, Sharon J.
author_sort Schweizer, Herbert P.
collection PubMed
description Genetic research into the select agents Burkholderia pseudomallei and B. mallei is currently hampered by a paucity of approved antimicrobial drug–selection markers. The strict regulations imposed on researchers in the United States but not in other parts of the world lead to discrepancies in practice, hinder distribution of genetically modified strains, and impede progress in the field. Deliberation and decisions regarding alternative selection markers (antimicrobial and nonantimicrobial drugs) by the international community, regulatory authorities, and funding agencies are needed.
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spelling pubmed-26307402009-02-09 Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei Schweizer, Herbert P. Peacock, Sharon J. Emerg Infect Dis Perspective Genetic research into the select agents Burkholderia pseudomallei and B. mallei is currently hampered by a paucity of approved antimicrobial drug–selection markers. The strict regulations imposed on researchers in the United States but not in other parts of the world lead to discrepancies in practice, hinder distribution of genetically modified strains, and impede progress in the field. Deliberation and decisions regarding alternative selection markers (antimicrobial and nonantimicrobial drugs) by the international community, regulatory authorities, and funding agencies are needed. Centers for Disease Control and Prevention 2008-11 /pmc/articles/PMC2630740/ /pubmed/18976550 http://dx.doi.org/10.3201/eid1411.080431 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Perspective
Schweizer, Herbert P.
Peacock, Sharon J.
Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title_full Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title_fullStr Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title_full_unstemmed Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title_short Antimicrobial Drug–Selection Markers for Burkholderia pseudomallei and B. mallei
title_sort antimicrobial drug–selection markers for burkholderia pseudomallei and b. mallei
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630740/
https://www.ncbi.nlm.nih.gov/pubmed/18976550
http://dx.doi.org/10.3201/eid1411.080431
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