Metagenomic Diagnosis of Bacterial Infections

To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient’s feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with...

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Detalles Bibliográficos
Autores principales: Nakamura, Shota, Maeda, Norihiro, Miron, Ionut Mihai, Yoh, Myonsun, Izutsu, Kaori, Kataoka, Chidoh, Honda, Takeshi, Yasunaga, Teruo, Nakaya, Takaaki, Kawai, Jun, Hayashizaki, Yoshihide, Horii, Toshihiro, Iida, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630750/
https://www.ncbi.nlm.nih.gov/pubmed/18976571
http://dx.doi.org/10.3201/eid1411.080589
Descripción
Sumario:To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient’s feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with this metagenomic approach.

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