Metagenomic Diagnosis of Bacterial Infections

To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient’s feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with...

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Detalles Bibliográficos
Autores principales: Nakamura, Shota, Maeda, Norihiro, Miron, Ionut Mihai, Yoh, Myonsun, Izutsu, Kaori, Kataoka, Chidoh, Honda, Takeshi, Yasunaga, Teruo, Nakaya, Takaaki, Kawai, Jun, Hayashizaki, Yoshihide, Horii, Toshihiro, Iida, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630750/
https://www.ncbi.nlm.nih.gov/pubmed/18976571
http://dx.doi.org/10.3201/eid1411.080589
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author Nakamura, Shota
Maeda, Norihiro
Miron, Ionut Mihai
Yoh, Myonsun
Izutsu, Kaori
Kataoka, Chidoh
Honda, Takeshi
Yasunaga, Teruo
Nakaya, Takaaki
Kawai, Jun
Hayashizaki, Yoshihide
Horii, Toshihiro
Iida, Tetsuya
author_facet Nakamura, Shota
Maeda, Norihiro
Miron, Ionut Mihai
Yoh, Myonsun
Izutsu, Kaori
Kataoka, Chidoh
Honda, Takeshi
Yasunaga, Teruo
Nakaya, Takaaki
Kawai, Jun
Hayashizaki, Yoshihide
Horii, Toshihiro
Iida, Tetsuya
author_sort Nakamura, Shota
collection PubMed
description To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient’s feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with this metagenomic approach.
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spelling pubmed-26307502009-02-09 Metagenomic Diagnosis of Bacterial Infections Nakamura, Shota Maeda, Norihiro Miron, Ionut Mihai Yoh, Myonsun Izutsu, Kaori Kataoka, Chidoh Honda, Takeshi Yasunaga, Teruo Nakaya, Takaaki Kawai, Jun Hayashizaki, Yoshihide Horii, Toshihiro Iida, Tetsuya Emerg Infect Dis Dispatch To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient’s feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with this metagenomic approach. Centers for Disease Control and Prevention 2008-11 /pmc/articles/PMC2630750/ /pubmed/18976571 http://dx.doi.org/10.3201/eid1411.080589 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Nakamura, Shota
Maeda, Norihiro
Miron, Ionut Mihai
Yoh, Myonsun
Izutsu, Kaori
Kataoka, Chidoh
Honda, Takeshi
Yasunaga, Teruo
Nakaya, Takaaki
Kawai, Jun
Hayashizaki, Yoshihide
Horii, Toshihiro
Iida, Tetsuya
Metagenomic Diagnosis of Bacterial Infections
title Metagenomic Diagnosis of Bacterial Infections
title_full Metagenomic Diagnosis of Bacterial Infections
title_fullStr Metagenomic Diagnosis of Bacterial Infections
title_full_unstemmed Metagenomic Diagnosis of Bacterial Infections
title_short Metagenomic Diagnosis of Bacterial Infections
title_sort metagenomic diagnosis of bacterial infections
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630750/
https://www.ncbi.nlm.nih.gov/pubmed/18976571
http://dx.doi.org/10.3201/eid1411.080589
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