Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through multi-target mechanisms, including inhibition of topoisomerase I, interaction with DNA and direct effects on mitochondr...

Descripción completa

Detalles Bibliográficos
Autores principales: Baunbæk, Dianne, Trinkler, Nolwenn, Ferandin, Yoan, Lozach, Olivier, Ploypradith, Poonsakdi, Rucirawat, Somsak, Ishibashi, Fumito, Iwao, Masatomo, Meijer, Laurent
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630805/
https://www.ncbi.nlm.nih.gov/pubmed/19172192
http://dx.doi.org/10.3390/md20080026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630805/
https://www.ncbi.nlm.nih.gov/pubmed/19172192
http://dx.doi.org/10.3390/md20080026

Ejemplares similares