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Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through multi-target mechanisms, including inhibition of topoisomerase I, interaction with DNA and direct effects on mitochondr...

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Detalles Bibliográficos
Autores principales:	Baunbæk, Dianne, Trinkler, Nolwenn, Ferandin, Yoan, Lozach, Olivier, Ploypradith, Poonsakdi, Rucirawat, Somsak, Ishibashi, Fumito, Iwao, Masatomo, Meijer, Laurent
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630805/ https://www.ncbi.nlm.nih.gov/pubmed/19172192 http://dx.doi.org/10.3390/md20080026

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