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Identification of two distinct structural regions in a human porcine endogenous retrovirus receptor, HuPAR2, contributing to function for viral entry
BACKGROUND: Of the three subclasses of Porcine Endogenous Retrovirus (PERV), PERV-A is able to infect human cells via one of two receptors, HuPAR1 or HuPAR2. Characterizing the structure-function relationships of the two HuPAR receptors in PERV-A binding and entry is important in understanding recep...
Autores principales: | Marcucci, Katherine T, Argaw, Takele, Wilson, Carolyn A, Salomon, Daniel R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630988/ https://www.ncbi.nlm.nih.gov/pubmed/19144196 http://dx.doi.org/10.1186/1742-4690-6-3 |
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