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SR proteins and the nonsense-mediated decay mechanism are involved in human GLB1 gene alternative splicing
BACKGROUND: The human GLB1 gene is known to give rise to two alternatively spliced mRNAs, which encode two different proteins: lysosomal β-galactosidase (β-gal) and elastin-binding protein (EBP). The β-gal transcript includes the 16 exons of the GLB1 gene. In the EBP transcript, exons 3, 4 and 6 are...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631023/ https://www.ncbi.nlm.nih.gov/pubmed/19114006 http://dx.doi.org/10.1186/1756-0500-1-137 |