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The application and use of chemical space mapping to interpret crystallization screening results

Macromolecular crystallization screening is an empirical process. It often begins by setting up experiments with a number of chemically diverse cocktails designed to sample chemical space known to promote crystallization. Where a potential crystal is seen a refined screen is set up, optimizing aroun...

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Detalles Bibliográficos
Autores principales: Snell, Edward H., Nagel, Ray M., Wojtaszcyk, Ann, O’Neill, Hugh, Wolfley, Jennifer L., Luft, Joseph R.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631111/
https://www.ncbi.nlm.nih.gov/pubmed/19018100
http://dx.doi.org/10.1107/S0907444908032411

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