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The application and use of chemical space mapping to interpret crystallization screening results
Macromolecular crystallization screening is an empirical process. It often begins by setting up experiments with a number of chemically diverse cocktails designed to sample chemical space known to promote crystallization. Where a potential crystal is seen a refined screen is set up, optimizing aroun...
Autores principales: | Snell, Edward H., Nagel, Ray M., Wojtaszcyk, Ann, O’Neill, Hugh, Wolfley, Jennifer L., Luft, Joseph R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631111/ https://www.ncbi.nlm.nih.gov/pubmed/19018100 http://dx.doi.org/10.1107/S0907444908032411 |
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