Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP

Folate derivatives are essential vitamins for cell growth and replication, primarily because of their central role in reactions of one-carbon metabolism. Folates require polyglutamation to be efficiently retained within the cell and folate-dependent enzymes have a higher affinity for the polyglutamy...

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Detalles Bibliográficos
Autores principales: Young, Paul G., Smith, Clyde A., Metcalf, Peter, Baker, Edward N.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631112/
https://www.ncbi.nlm.nih.gov/pubmed/18566510
http://dx.doi.org/10.1107/S0907444908012262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631112/
https://www.ncbi.nlm.nih.gov/pubmed/18566510
http://dx.doi.org/10.1107/S0907444908012262

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