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Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP
Folate derivatives are essential vitamins for cell growth and replication, primarily because of their central role in reactions of one-carbon metabolism. Folates require polyglutamation to be efficiently retained within the cell and folate-dependent enzymes have a higher affinity for the polyglutamy...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631112/ https://www.ncbi.nlm.nih.gov/pubmed/18566510 http://dx.doi.org/10.1107/S0907444908012262 |