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5-HT(2C)Rs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis

Drugs activating 5-hydroxytryptamine 2C receptors (5-HT(2C)Rs) potently suppress appetite, but the underlying mechanisms for these effects are not fully understood. To tackle this issue, we generated mice with global 5-HT(2C)R deficiency (2C null) and mice with 5-HT(2C)Rs re-expression only in pro-o...

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Detalles Bibliográficos
Autores principales:	Xu, Yong, Jones, Juli E., Kohno, Daisuke, Williams, Kevin W., Lee, Charlotte E., Choi, Michelle J., Anderson, Jason G., Heisler, Lora K., Zigman, Jeffrey M., Lowell, Bradford B., Elmquist, Joel K.
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2008
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631191/ https://www.ncbi.nlm.nih.gov/pubmed/19038216 http://dx.doi.org/10.1016/j.neuron.2008.09.033

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