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Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice

BACKGROUND: Complement represents a crucial mediator of neuroinflammation and neurodegeneration after traumatic brain injury. The role of the terminal complement activation pathway, leading to generation of the membrane attack complex (MAC), has not been thoroughly investigated. CD59 is the major re...

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Detalles Bibliográficos
Autores principales:	Stahel, Philip F, Flierl, Michael A, Morgan, B Paul, Persigehl, Ivonne, Stoll, Christiane, Conrad, Claudia, Touban, Basel M, Smith, Wade R, Beauchamp, Kathryn, Schmidt, Oliver I, Ertel, Wolfgang, Leinhase, Iris
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631471/ https://www.ncbi.nlm.nih.gov/pubmed/19133139 http://dx.doi.org/10.1186/1742-2094-6-2

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